Supposing should Caitlin ever become a werewolf on the Flash, I have a feeling she’ll not only become one due to curing herself of ALS but also to avenge her rape and torture (of her pets) to the point of having to acquire their DNA and those of wolves to get her revenge. However her anger gets the better of her, believing that it’s Barry Allen who raped her and she goes on trying to kill him. If that doesn’t succeed, she kills and then impersonates Iris West.
In a way, she’s the villain Harrison Wells’s supposed to be in the sense of being the biggest traitor Team Flash’s got and also the unpredictable. That’s also a crucial plot point in Alan Moore’s take on Marvelman (himself derivative of Shazam) and his unpublished Twilight of the Superheroes proposal. In the latter, there’s a similar plot point about Billy Batson going unstable and giving into his baser tendencies (Johnny Bates).
Then he gets killed and impersonated by Martian Manhunter who in turn gets killed by Superman. In the Flash, these plot points recur with Caitlin being raped and having had her dogs killed she uses their DNA and that of wolves to become an angry animal herself allying herself with wolves to torment humanity for what they did to her. Then she impersonates her victim until she and her pets get killed by Barry (there goes the JJBA undertones though its own author might regret that).
In turning Caitlin into an angry werewolf seeking revenge for the abuse she’s endured and then abusing people herself (that’s even the case in real life), she becomes the Magdalene to Felicity’s Madonna. But in the sense of Caitlin having fallen from humanity and becoming even more vicious as to give into her baser tendencies whilst Felicity overtook Black Canary as Oliver’s girlfriend and is idolised too much.
Maybe that’s a bad analogy but enough to differentiate the two women. One goes evil from being abused, the other develops divine powers (though that’s what’ll happen to Patty should she reappear on the Flash as Big Barda). To make matters worse, Patty/Big Barda tries to resurrect Caitlin but with the odd side effect of her becoming purely evil and attempting to corrupt Cisco.
(When you think about it, that’s also a big plot point in Marv Wolfman’s Teen Titans where Raven also repeatedly gives into her baser tendencies, at least twice in his writings where the second time she goes evil and then dies only to reappear as a golden ghost.)
Caitlin becomes so evil that she corrupts Patty Spivot and turns her into her minion (that’s practically what Raven did to Starfire). Barry Allen however kills both of them, thus risking a lot of outcry. Never mind that’s also making Patty Spivot less of a Mary Sue but in the sense of resurrecting somebody so heinous that she worsens because of it (and Caitlin would turn Felicity into a hyena).
Should it occur, Caitlin becomes the biggest villain to date and is the Magdalene to Felicity’s Madonna in having a very fallen reputation, prone to evil and stuff. (Felicity, prior to becoming a hyena, is very idealised.)